The sins of the father are to be laid upon the children. Dr Victor Frankenstein thought he had seen the last of his monsters when they promised to stay away from humanity, but in the twilight years of his life his hopes are shattered. Years after their departure, news of a horrific and seemingly inhuman massacre reaches him and he fears it is his ‘children’ who are responsible. With his natural son Vincent by his side, he vows to discover the truth and if necessary, to destroy his monstrous creations once and for all. When Vincent becomes separated from his father, he meets Mary, an idealistic and free-thinking peasant, and John Idaho Thatcher, an enigmatic explorer-cum-cowboy with a strange cogged and wired waistcoat and steed like no other. Together, they must battle not only Frankenstein’s monsters who look to wage war on the living with their warped perceptions of humanity, but also their own fears and personal demons.